USCAST is part of a global network dedicated to fighting the rise of antibiotic resistance through scientific, educational, and policy-creating activities.
We recognize an increasing need to create a path to evaluate both new and old antibacterial agents in the current context of antibacterial resistance, extent of tissue penetration at the site of infection, and bacterial killing rate at that body site.
Our mission is to work with our global partners, establishing crucial standards for testing and interpreting the activity of antibacterial agents. The standards established by USCAST are intended to provide support for healthcare providers to use the safest and most effective antibacterial agents to save lives.
Unlike other STIC setting organizations, USCAST does not aim to provide comprehensive pathogen-drug breakpoint tables, but rather focuses the expertise of our membership on both generating new evidence and interpreting imperfect existing data to address the most challenging breakpoint controversies.
Jason M. Pogue, Pharm. D.
Chairman
University of Michigan College of Pharmacy
Sujata M. Bhavnani, Pharm. D., MS
Vice Chair
Institute for Clinical Pharmacodynamics
Paul G. Ambrose, Pharm. D.
Treasurer
Institute for Clinical Pharmacodynamics
David R. Andes, MD
University of Wisconsin
Ronald N. Jones, MD
Emeritus Member
Thomas P. Lodise, Pharm. D., Ph.D.
Albany College of Pharmacy & Health Sciences
Helio S. Sader, MD, Ph.D.
Element Iowa City (JMI Laboratories)
John S. Bradley, MD
University of California San Diego Rady Children’s Hospital
Alexander J. Lepak, MD
University of Wisconsin School of Medicine and Public Health
Emil P. Lesho, DO
Infectious Diseases Unit Rochester Regional Health
Erin K. McCreary, Pharm. D.
University of Pittsburgh Medical Center
Robert R. Rennie, Ph.D.
University of Alberta Hospital
Stefan Riedel, MD, Ph.D.
Harvard Medical School
Keith A. Rodvold, Pharm. D.
University of Illinois at Chicago College of Pharmacy
Michael J. Rybak, Pharm. D., Ph.D.
Wayne State University
Marc Scheetz, Pharm. D., MSc
Midwestern University
Olga Lomovskaya, Ph.D.
Qpex Biopharma
Denver T. Niles, MD
Texas Children's
Ryan K. Shields, Pharm. D.
University of Pittsburgh Medical Center
Judith Steenbergen, Ph.D.
Scientific and Medical Affairs Consulting (SMAC)
The below schematic represents the USCAST process for STIC assessment. While our membership ultimately votes on STIC, interested stakeholders are a critically important part of our STIC-setting process. We encourage interested parties to participate in our annual virtual meetings at which STIC recommendations are initially presented and provide feedback on the proposals. Final STIC recommendations will be based on objective consideration of any feedback received.
While the executive committee is responsible for the final decisions on what STIC to prioritize for assessment, we encourage feedback from our members and the community at large regarding clinically important STIC that need to be reassessed. If you have a STIC recommendation for USCAST to consider, please contact us here.